Health Condition 1: null- shivering post neuraxial anaesthesia
Conditions
Interventions
Intervention1: Ketamine- 0.25mg/kg via IV route
Midazolam- 5mcg/kg via IV route
Pethidine- 0.35mg/kg via IV route: All the 3 drugs are given as a bolus dose once immediately after spinal anaesthesia.
Sponsors
Kasturba Medical College
Eligibility
Inclusion criteria
Inclusion criteria: ASA physical status 1 and 2 patients who are scheduled for elective lower abdominal and lower limb surgeries under spinal anaesthesia.
Exclusion criteria
Exclusion criteria: Patient refusal, Severe systemic disorders like diabetes mellitus, hypertension, cardiopulmonary disease, etc. Body mass index of >=30 kg/m2, Known history of alcohol or substance abuse. Renal insufficiency, Peptic ulcer disease, Thyroid disease, Psychiatric disorder, Pregnancy, Acute infections e.g. upper respiratory tract infection or urinary tract infection etc., and fever due to any other cause. Allergy to any of the study drugs and all known contraindications to spinal anaesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Incidence and grading of intraoperative shivering. 2. Core body temperature and body surface temperatureTimepoint: After spinal anaesthesia, every 10 minutes for 60 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Measurement of vital signs- HR, Blood pressure, Mean arterial pressure, SPO2. 2. Adverse effects- hypotension, hallucination, nausea and vomitingTimepoint: Every 5 minutes for 30 minutes | — |
Countries
India
Contacts
Public ContactDr Lakshmi Sagar V
Kasturba Medical College, Mangalore, Manipal University
Outcome results
None listed