High Flow Nasal Therapy delivered as a standard of care in ICU

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/01/011427

Enrollment

300

Registered

2018-01-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ICU patients requiring oxygen therapy

Interventions

Intervention1: Nasal High Flow (NHF): NHF delivered using the flow source AIRVO Control Intervention1: Standard O2 therapy: Using conventional devices

Eligibility

Inclusion criteria

Inclusion criteria: All adults over 18 years

Exclusion criteria

Exclusion criteria: 1. Altered sensorium (GCS 2. Not able to protect airways 3. Nasal obstruction (anatomical, does not include RT) 4. Patient Refusal 5. Unstable hemodynamics like double vasopressors support, intractable arrhythmias 6. Respiratory arrest 7. Facial injury 8. Recent upper gastrointestinal or oropharyngeal surgery 9. Epistaxis 10. Base of skull fracture 11. 12. Any contraindication to CPAP

Design outcomes

Primary

Measure	Time frame
Need for escalation mechanical (invasive/ non-invasive) ventilationTimepoint: During ICU admission	—

Secondary

Measure	Time frame
Hospital acquired pneumonia Timepoint: after 48 hrs of admission ;Hospital LOS Timepoint: During hospital admisson;LOS ICU Timepoint: ICU admission;Mortality Timepoint: During ICU admission	—

Countries

India

Contacts

Public ContactYatin Mehta

Medanta The Medicity

yatinmehta@hotmail.com1244141414

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026