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Use of beneficial bacteria in the treatment of bone loss around teeth

Clinical efficacy of local administration of biodegradable probiotic fibres (Lactobacillus reuteri) as an adjunctive to nonsurgical periodontal therapy - a clinico- microbiological study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011422
Enrollment
40
Registered
2018-01-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- localised chronic periodontitis

Interventions

Intervention1: Biodegradable probiotic fibres (lactobacillus reuteri): Probiotics are the live micro-organisms principally bacteria which, when administrated in adequate amounts confer a health benefi

Sponsors

Vanditha D
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient with chronic periodontitis as clinically evidenced by gingivitis together with mild to moderate periodontal pockets 2.Clinically and radiographically evidence of bone loss 3.Should have at least probing depth of more than 5mm.

Exclusion criteria

Exclusion criteria: 1.Patients with ongoing antibiotic therapy 2.Patients with systemic diseases history of diabetes, liver and kidney disease, neurological deficiencies 3.Pregnancy, lactating and smoking 4.Patients undergone surgical or nonsurgical therapy with in 6 months prior the study. 5.Patients with periapical abscess or periodontal abscess. 6.Patients who are deemed to be uncooperative. 7.Patients with poor oral hygiene.

Design outcomes

Primary

MeasureTime frame
pocket depthTimepoint: 3 months

Secondary

MeasureTime frame
clinical attachment level plaque index gingival index modified sulcular bleeding indexTimepoint: 3 months

Countries

India

Contacts

Public ContactDrB V Ramesh Reddy

Narayana dental college

perioramesh@yahoo.co.in9849798990

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026