Hair follicle and skin cell transplantation for treatment of stable vitiligo

Efficacy and safety of non-cultured extracted outer-root sheath cell suspension and conventional epidermal cell suspension transplantation in stable vitiligo and correlation with constituent stem cell populations.

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/01/011411

Enrollment

Registered

2018-01-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Vitiligo

Interventions

Intervention1: Non cultured extracted follicular outer root-sheath cell suspension (NCEF ORS CS).: The number of cells transplanted would vary from 2 lacs to 2 million or 3 million depending on size o

Eligibility

Inclusion criteria

Inclusion criteria: Patients with clinical diagnosis of segmental or generalized vitiligo which has been stable for at least one year or more.

Exclusion criteria

Exclusion criteria: i.Age less than 12 yrs ii.Pregnant women iii.Patient with actively spreading vitiligo iv.Appearance of new lesions v.Koebnerization vi.Keloid or bleeding diathesis vii.Active infection at the site

Design outcomes

Primary

Measure	Time frame
Percentage re-pigmentationTimepoint: Six months	—

Secondary

Measure	Time frame
Number of melanocytes, melanocyte stem cells, mesenchymal stem cells, keratinocyte stem cells, adipose stem cells in cell suspensionTimepoint: 1 week	—

Countries

India

Contacts

Public ContactSomesh Gupta

All India Institute of Medical Sciences, New Delhi

someshgupta@hotmail.com011-26546626

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026