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Bone marrow(inactive) sparing Whole Pelvic Intensity Modulated Radiation Therapy(IMRT) followed by Image Guided Brachytherapy(IGBT) in locally advanced cervical cancer. A prospective study

Whole Pelvic Intensity Modulated Radiation Therapy(IMRT) combined with Image Guided Brachytherapy(IGBT) for locally advanced cervical cancer. A prospective study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/01/011380
Enrollment
20
Registered
2018-01-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- 1) Biopsy proven carcinoma of cervix 2) Age : more than 18-65 yrs 3) FIGO Stage IIB - IIIB 4) Karnofsky performance scale score 70 or above 5) Normal kidney, liver and bone marrow function

Interventions

None listed

Sponsors

Department of Radiotherapy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Biopsy proven carcinoma of cervix 2) Age : more than 18-65 yrs 3) FIGO Stage IIB - IIIB 4) Karnofsky performance scale score 70 or above 5) Normal kidney, liver and bone marrow function 6) Patient who have given informed consent

Exclusion criteria

Exclusion criteria: Early stage cancer FIGO stage IA -IIA 2) Metastatic patients 3) Lack of Histopathological proof of malignancy 4) Doubtful follow-up and /or non-compliance 5) Uncontrolled co-morbid conditions e.g. Hypertension, Diabetes Mellitus, Chronic Obstructive pulmonary disease (COPD), coronary artery disease (CAD), Severe Mental or Physical Disorder 6) Pregnancy 7) Deranged renal, liver function test 8) Patient refusing to give written informed consent 9) H/O- of previous irradiation 10) H/O-of allergy 11)Collagen vascular disease

Design outcomes

Primary

MeasureTime frame
To evaluate the loco-regional control , short term survival and also dosimetry comparison between conventional and image â?? guided and volume â?? optimized Brachytherapy planning in patients of locally advanced carcinoma cervix treated with WP-IMRT combined with image guided Brachytherapy (IGBT). 2. To assess the acute & late toxicity in patients of locally advanced carcinoma cervix treated with WP-IMRT combined with image guided Brachytherapy (IGBT).Timepoint: TREATMENT COMPLETE WITHIN 8WKS.—

Secondary

MeasureTime frame
To assess the acute & late toxicity in patients of locally advanced carcinoma cervix treated with WP-IMRT combined with image guided Brachytherapy (IGBT).Timepoint: TREATMENT COMPLETE WITHIN 8WKS—

Countries

India

Contacts

Public ContactRam Pukar Bharat

All India Institute of Medical Sciences, New Delhi

sharmadn@hotmail.com9868398313

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026