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A clinical study to compare the effect of 0.074% Diclofenac sodium mouthwash and 50 mg diclofenac sodium tablet in reduction of pain and swelling after gum surgery for pyorrhea.

A randomized prospective split-mouth clinical study to compare the post-operative analgesic and anti-inflammatory effect of diclofenac sodium (0.074% mouthwash or 50mg tablets) after periodontal flap surgery.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011352
Enrollment
30
Registered
2018-01-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients indicated for conventional periodontal flap surgery

Interventions

Intervention1: Diclofenac Sodium 0.074% mouthwash: After periodontal flap surgery either 0.074% diclofenac sodium mouthwash will be given or 50 mg tablet of same drug will be given. And analgesic and

Sponsors

None
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients having periodontal pocket depth ranging from 5mm to 8mm. 2. Patients indicated for periodontal surgery bilaterally in same arch. 3. Systemically healthy patients.

Exclusion criteria

Exclusion criteria: 1. Patients having endo-perio lesions. 2. Patients requiring resective osseous surgery or regenerative osseous surgery. 3. Patients with the history of intolerance or hypersensitivity to diclofenac. 4. Any systemic diseases or condition that affects the oral tissues, 5. Pregnant or lactating women. 6. Acute gingival or periodontal disease. 7. Patients on oral/systemic NSAIDs therapy for the last three months.

Design outcomes

Primary

MeasureTime frame
Diclofenac sodium local application (0.074% mouthwash) will have equal analgesic effect as compared to its systemic administration (tablet), but it would be better in terms of its anti-inflammatory effect and patientâ??s acceptability when used after periodontal flap surgery.Timepoint: Analgesic effect will checked on 1st 2nd 3rd and 4th day after surgery. Inflammation will be assessed after 7 days 1 month and 3 months after surgery.—

Secondary

MeasureTime frame
NoneTimepoint: None—

Countries

India

Contacts

Public ContactDr Shreeprasad V Wagle

MGVs KBH Dental College and Hospital

agrodent@rediffmail.com9822107562

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026