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How much should be the gap between feeding for low birth weight babies

TWO-HOURLY VERSUS THREE-HOURLY FEEDING FOR VERY LOW BIRTH-WEIGHT INFANTS: A RANDOMIZED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011320
Enrollment
350
Registered
2018-01-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- feeding interval in very low birth weight babies

Interventions

Intervention1: Three hourly feeding: It avoid persistent hyperemia in gut and decrease residual before next feed Control Intervention1: Two hourly feeding: It reduces distension of gut and results in

Sponsors

None
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Al inborn neonates weighing between 1000-1500g in whom enteral feeding would be started within 96 hours of life

Exclusion criteria

Exclusion criteria: 1-Major congenital malformation including Tracheo-Esophageal Fistula, Oesophageal Atresia, Duodenal atresia interfering or delaying the feed initiation. 2-Chromosomal abnormalities, 3-Perinatal asphyxia (APGAR score of reason, ï?? out born status, ï?? Intestinal perforation before initiation of feeding, ï?? Infants with Absent or Reversed End Diastolic Flow(AEDF/REDF) in antenatal USG ï?? Infants who are severely sick, on invasive ventilation or shock, ï?? Infants in whom enteral feeding could not be started within 96 hours of life.

Design outcomes

Primary

MeasureTime frame
Time (days) needed to achieve full enteral feed.Timepoint: 1 week

Secondary

MeasureTime frame
To study and compare the incidence of feed intolerance, hypoglycaemia and NEC stage 2 or 3Timepoint: 1 week

Countries

India

Contacts

Public ContactDr P K Debata

VMMC and Safdarjung Hospital

drpkdebata@gmail.com7291000664

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026