Effect of blood pressure lowering medicines on function of blood vessels in elderly patients with high blood pressure

An observational study of the effect of first line anti-hypertensive drugs on endothelial function in newly diagnosed elderly hypertensive patients - HTNEND trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2018/01/011306

Enrollment

Registered

2018-01-12

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Hypertension

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Newly diagnosed elderly hypertensive patients 2. Who give consent for the study

Exclusion criteria

Exclusion criteria: 1. Patients who do not give consent 2. Already diagnosed case of Hypertension i.e. on treatment 3. Past h/o Coronary artery disease 4. Past h/o Cerebrovascular accident 5. Moderate to severe renal dysfunction,i.e. with creatinine clearance 6. Patient taking any anti-dyslipidemic or any antiplatelet drugs

Design outcomes

Primary

Measure	Time frame
Improvement in endothelial function assessed by flow mediated dilatation of brachial arteryTimepoint: 0 at baseline and after 1 month of treatment	—

Secondary

Measure	Time frame
Blood pressure lowering effect and safety analysisTimepoint: 0 and 1 month	—

Countries

India

Contacts

Public ContactDr Ashis Kumar Choudhury

IMS BHU

iac2k10@gmail.com9415255998

Outcome results