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Glucose related protein 78(GRP78) as a biomarker in patients of kidney cancer.

Identification of Glucose related protein 78(GRP78) as a biomarker for tumor behavior in patients of renal cell carcinoma (RCC).

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/01/011291
Enrollment
60
Registered
2018-01-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients already diagnosed as renal cell carcinoma(RCC) and already plan for surgery

Interventions

None listed

Sponsors

AIIMS Delhi Intramural project
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with provisional diagnosis of RCC and plan for partial/radical nephrectomy.

Exclusion criteria

Exclusion criteria: Patients with concomitant second malignancy and patients in which adjacent normal renal tissue is not available for sampling during surgery.

Design outcomes

Primary

MeasureTime frame
To study the mRNA and protein expression of GRP78 in tumor and adjacent non malignant kidney tissue of RCC patients and compare the levels. -To study the expression of GRP78 in serum of RCC patients and compare with age and gender matched controls. - To correlate the levels of GRP78 with stage and grade of RCC.Timepoint: 2 year—

Secondary

MeasureTime frame
To correlate the levels of GRP78 with stage and grade of RCC.Timepoint: 2 year—

Countries

India

Contacts

Public ContactDR MANOJ KUMAR

AIIMS, Delhi

drmanoj1611@yahoo.com9871195787

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026