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To compare efficacy of two drugs in maintaining pupillary dilatation during Phaco emulsification surgery.

Efficacy of Nepafenac 0.1% versus Flurbiprofen 0.03% in maintaining intraoperative mydriasis during Phaco emulsification. A comparative study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011277
Enrollment
160
Registered
2018-01-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with Cataract

Interventions

Intervention1: Non steroidal antiinflammatory eye drops: Arm - B Flurbiprofen 0.03% eye drop.One drop topically at an interval of 15 minutes four times.This is done once on the day of surgery preoper

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Cataract patients 40 yrs age and above

Exclusion criteria

Exclusion criteria: 1) Diabetes Mellitus and Hypertension 2) Ocular co-morbidities like injury, uveitis and local pupillary abnormalities 3) Any previous intraocular surgery 4) Pseudo-exfoliation 5) Eye with 6) Intra-operative surgical complications such as posterior capsular tear, vitreous loss, nucleus drop, zonular dehiscence 7) Pregnant and nursing mothers. 8) Knowledge or suspicion of allergy or hypersensitivity to preservatives, steroids, topical NSAIDS or any other component of study medications. 9) Use of any eye medications except artificial tear drops 3 weeks prior to inclusion in the study. 10) Use of alpha 1 receptor blocker (Tamsulosin) or tricyclic antidepressants (TCA) that may induce intra-operative miosis. 11) Use of systemic NSAIDS or steroids within 4 weeks prior to inclusion in the study.

Design outcomes

Primary

MeasureTime frame
Measuring difference in reduction of papillary size using two different drugs. Timepoint: At beginning of surgery, After phacoemulsification, After completion of surgery

Secondary

MeasureTime frame
NilTimepoint: Nil

Countries

India

Contacts

Public ContactDr Ankur K Shrivastava

Aiims Raipur

shrivastavadrankur@gmail.com9713100777

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026