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comparative evaluation of the effects of Bovine derived xenograft (osseograft TM) and combination of bovine derived xenograft and calcium sulphate hemihydrate (osseograftTM) , used for the treatment of bone defects due to diseases of gums, clinically and using radiograph

Comparative Clinical and Radiographic Evaluation of the Effect of Bovine Derived Xenograft (OsseograftTM) Alone Vs A Combination of Bovine Derived Xenograft and Calcium sulphate hemihydrate (OsseomoldTM) in the Treatment of Intrabony Defects in Chronic Periodontitis Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011245
Enrollment
40
Registered
2018-01-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Chronic Periodontitis patients with interproximal bone defects of 5mm or more Health Condition 2: R688- Other general symptoms and signs

Interventions

Intervention1: bovine derived xenograft plus calcuim sulphate hemi hydrate: commercially available as Osseomold TM Control Intervention1: Bovine derived Xenograft: commercially available as Osseograft

Sponsors

Nikita Dilip Patil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Age group between 20-60 2) Diagnosis with chronic periodontitis 3) Patients in good systemic health with no contraindication to periodontal surgery 4) Patients having Intrabony defects with pocket depths of >5mm and with radiographic evidence of vertical / angular bone loss in the affected sites. 5) Involved teeth to be vital and asymptomatic

Exclusion criteria

Exclusion criteria: 1) One â?? wall osseous defects. 2) Patients suffering from any systemic diseases or with compromised immune system. 3) Patients who had received any type of periodontal therapy for the past 6 months 4) Patients taking any immuno-suppressive drugs like corticosteroids 5) Patients with a known history of allergy to doxycycline or Chlorhexidine or any other medicine are used in the study. 6) Patients showing unacceptable oral hygiene compliance during / after the phase I therapy. 7) Patients taking any drug known to cause gingival enlargement. 8) Pregnant and/or lactating mothers. 9) Patients who were smokers or had tobacco in any other form. 10) Endodontically treated teeth. 11) Patient on anticoagulant therapy 12) Patient with bleeding disorders.

Design outcomes

Primary

MeasureTime frame
1 Probing Pocket Depth 2 Clinical Attachment Level 3 Plaque Index (Turskey Gilmore-Glickman Modification of Quigley Hein) 4 Gingival Index (Loe & Silness, 1963)Timepoint: the outcomes will be assessed pre-operatively, immediate post operatively, 3 months post operatively and 6 month post operatively—

Secondary

MeasureTime frame
Radiographic bone fill will be evaluated using intra oral periapical radiographs of the surgical siteTimepoint: radiographs will be taken at baseline post surgery and 6 months post surgery—

Countries

India

Contacts

Public ContactNikita Dilip Patil

Nair Hospital Dental College

maladixit25@gmail.com9699696160

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026