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Comparison of Articaine with Lignocaine for extraction of maxillary teeth

Comparison of Local Anaesthesia by Single Buccal Infiltration of Anaesthetic Agent 4% Articaine (with 1:100000 Adrenaline) with Routine Buccal and Palatal Infiltration of 2% Lidocaine (with 1:200000 Adrenaline) for the Extraction of Maxillary Premolar Teeth

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011239
Enrollment
100
Registered
2018-01-10
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Extraction of maxillary premolars for orthodontic treatment

Interventions

Intervention1: 4 % Articaine [with 1:100000 Adrenaline] local anaesthetic solution: Buccal supra periosteal infiltration (1.7 ml) of 4% Articaine with 1:100000 Adrenaline on the other. The injections

Sponsors

Vikas Sandilya Self
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Any patient who required bilateral extractions of maxillary first or second premolars indicated for orthodontic treatment under local anaesthesia.

Exclusion criteria

Exclusion criteria: 1) Known or suspected allergies or sensitivities to sulfites, amide type local anesthetics or any ingredients in the anesthetic solution. 2) Concomitant cardiac or neurological disease. 3) Pregnancy / lactation. 4) Concomitant use of monoamine oxidase inhibitors, tricyclic antidepressants, phenothiazine, vasodepressor drugs or ergot type oxytocic drugs. 5) Subjects who were on sedatives. 6) Subjects who had taken aspirin, acetaminophen, NSAIDS 24 hours prior to administration of local anesthetic. 7) Inability to give Informed consent.

Design outcomes

Primary

MeasureTime frame
a) The efficacy of only buccal infiltration of 4 % Articaine in extraction of maxillary premolars and to compare this with the efficacy of routine buccal and palatal infiltration of Lignocaine on the opposite side. b) Onset of anaesthesia c) Duration of action d) Prolonged anaesthesia or paraesthesia with 4 % Articaine in comparison to 2 % Lignocaine.Timepoint: 5 minutes after injection local anaesthetic, immediately after dental extraction and 1 hour after dental extraction

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactPaul Mathai

Nair Hospital Dental College

paulmathai89@gmail.com9920018553

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026