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Efficacy of morphine and dexmedetomidine as adjuvants to levobupivacaine in spinal anaesthesia for abdominal hysterectomy

Comparison of morphine and dexmedetomidine as adjuvants to isobaric levobupivacaine for spinal anaesthesia in patients undergoing abdominal hysterectomy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011178
Enrollment
70
Registered
2018-01-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- All participant will either be ASA ( American Society of Anaesthesiologist ) grade 1 or 2

Interventions

Intervention1: Dexmedetomidine: It is a highly selective α2 adrenergic receptor agonist, now emerging as an adjuvant to regional anaesthesia, where evolving studies can build evidence for its safe us

Sponsors

AIIMS Raipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA 1 or 2 patients 2. 18 - 60 yrs of age 3. Patient undergoing abdominal hysterectomy under subarachnoid block

Exclusion criteria

Exclusion criteria: a) Patients with contraindications for spinal anaesthesia b) ASA grade III and above c) Known allergy to any of the study medications d) Acute or chronic respiratory disease e) Hypertension or other cardiovascular abnormalities f) Cognitive or psychiatric disturbances g) Patients taking α adrenergic receptor antagonist, ACE inhibitors, angiotensin receptor blockers, chronic opioid therapy

Design outcomes

Primary

MeasureTime frame
we will compare analgesic efficacy of two drugs which are used for control of pain for hysterectomyTimepoint: intraoperative and postoperative upto 24 hrs

Secondary

MeasureTime frame
Adverse effects Vital parametersTimepoint: Intraoperative and postoperative upto 24 hrs

Countries

India

Contacts

Public ContactDr Mayank Kumar

AIIMS Raipur

mayanksonupmch@gmail.com9971760416

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026