To evaluate the effect of tulsi leaf extract containing gel in treating patients with gum disease

Comparative evaluation of Antimicrobial and Anti-gingivitis effect of Ocimum sanctum Linn. gel with 0.2% Chlorhexidine gel- A double blind placebo controlled randomized trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/01/011175

Enrollment

Registered

2018-01-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- moderate to severe gingivitis Health Condition 2: R688- Other general symptoms and signs

Interventions

Intervention1: tulsi leaf extract based gel: tulsi leaf will be shade dried and powdered. the extract will be taken from the powder and the gel will be formulated. after thorough oral prophylaxis pati

Eligibility

Inclusion criteria

Inclusion criteria: 1.presence of a minimum of 24 functional teeth 2.patients with moderate to severe form of gingivitis 3.patients withtin the age group of 18-45 years

Exclusion criteria

Exclusion criteria: 1.Subjects with removable or fixed orthodontic appliances or prosthesis. 2.Subjects who have been prescribed antibiotics or anti-inflammatory drugs in the past 3-6 months 3.Patients with any systemic involvement 4.Subjects with any reported allergy 5.Subjects with any tobacco related habits 6. Pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
The antimicrobial and anti-gingivitis effect of tulsi leaf extracr based gel will be evaluated by assesssing the plaque samples and improvement in the clinical parametersTimepoint: recall intervals of 15 days and 3 months	—

Secondary

Measure	Time frame
plaque index gingival index modified sulcus bleeding indexTimepoint: recall intervals of 15 days and 3 months follow up	—

Countries

India

Contacts

Public ContactDr Jothi M Varghese

Manipal College of Dental Sciences, Manipal

jothimv@gmail.com9845208532

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026