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Study comparing two methods of abortion in second trimester using misoprostol or ethacridine lactate after priming with mifepristone

A prospective comparative study of mifepristone followed by misoprostol or ethacridine lactate and oxytocin for second trimester abortions

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/01/011157
Enrollment
60
Registered
2018-01-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- SECOND TRIMESTER ABORTIONS

Interventions

Intervention1: Ethacridine lactate and Oxytocin: 1.Women were given 200mg mifepristone orally and 36 hours later patients were called to the hospital and admitted. 2.In the minor operation theatre the

Sponsors

Project in the Department of Obstetrics and Gynecology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Second trimester abortions for medical, social, eugenic reasons 2.Intrauterine pregnancy 3.18-40 years 4.Consent to participate in the study

Exclusion criteria

Exclusion criteria: 1.Less than 13 weeks and more than 20 weeks pregnancy terminations 2.Patients with history of renal disease or hepatic disease or bronchial asthma or hematological disease or glaucoma or heart disease etc 3.Hemoglobin less than 10 gm/dl 4.Patients with previous caesarean section and other uterine scars 5.Symptomatic reproductive tract infections 6.Hypersensitivity to mifepristone or misoprostol or ethacridine lactate or oxytocin 7.Rupture of membranes

Design outcomes

Primary

MeasureTime frame
1. Success rate ( percentage of complete abortions within 24 hours of using the drug ). 2. Induction abortion interval (the time from usage of misoprostol/ethacridine to expulsion of fetus and placenta) Timepoint: 11. Success rate ( percentage of complete abortions within 24 hours of using the drug ). 2. Induction abortion interval (the time from usage of misoprostol/ethacridine to expulsion of fetus and placenta)—

Secondary

MeasureTime frame
1. Side effects ( nausea, vomitting, flatulence, dyspepsia, diarrhea, constipation, headache, heavy menstrual bleeding, hypersensitivity, pyrexia, etc.) 2. Patients satisfaction and pain ( numerical scale) 3. Requirement of check curettage 4. Difference of pre procedure and post procedure hematocrit 5. Blood loss and requirement of transfusion.Timepoint: NONE—

Countries

India

Contacts

Public ContactDr Vatsla Dadhwal

AIIMS NEW DELHI

vatslad@hotmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026