Health Condition 1: null- Acute Non-Perforated Appendicitis in Children
Conditions
Interventions
Intervention1: A.Conservative Management Group (CMx): Broad spectrum intravenous antibiotics (Ceftriaxone 50 mg/kg/dose 12 hourly, Amikacin 7.5 mg/kg/dose 12 hourly and Metronidazole 10 mg/kg/dose 8 h
Sponsors
All India Institute of Medical Sciences Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age between 3 to 14 years both male and female. 2.Symptoms of Pain Abdomen, Anorexia, Nausea, Vomiting, Fever. 3.Signs of Focal Peritonitis (Guarding, Rebound tenderness) in Right Iliac Fossa (RIF). 4.Laboratory Findings of â?? Total Leukocyte Count, â?? Neutrophil count, â?? CRP, â?? LRG. 5.Abdominal Ultrasonogram s/o noncompressible nonperistaltic tubular structure >= 6 mm in AP diameter in RIF, probe tenderness in RIF, hyperechoic pericaecal fat & free fluid. 6.Abdominal CT scan suggestive of acute nonperforated appendicitis
Exclusion criteria
Exclusion criteria: 1.History of Recurrent Appendicitis 2.History of Chronic , Intermittent abdominal pain 3.Diffuse abdominal tenderness on clinical evaluation 4.Generalized Septicemia , Other Systemic illnesses 5.Abdominal Ultrasonography s/o Appendicolith, Appendicular Perforation ,Periappendicular Abscess or Phlegmon , Pan-peritonitis
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| a)Length of Stay in the Hospital b)Cost of Treatment c)Perforation Rate in CMx group d)Lump formation in CMx group e)Appendicular Abscess in CMx group f)Intraoperative Complications in SMx group g)Wound Complications in SMx group h)Negative Appendectomy Rate in SMx group i)Disability Days for the Child and Parents j)Missed School Days k)Measures of Quality of Life (PedsQLTM survey) l)Health Care Satisfaction (1 to 10 score) m)Recurrence Rate of Appendicitis in CMx groupTimepoint: All the children enrolled in the CMx group will be called / telephoned for follow up at 1 month, 3 months and 1 year interval. | — |
Primary
| Measure | Time frame |
|---|---|
| The feasibility and safety of the Conservative Management (CMx) with Antibiotics in children with acute Nonperforated Appendicitis.Timepoint: 1st Month - Feasibility assessment 6th Month - Mid-recruitment review 1 year - Final assessment. | — |
Countries
India
Contacts
Public ContactDr Bikasha Bihary Tripathy
All India Institute of Medical Sciences, Bhubaneswar
Outcome results
None listed