Health Condition 1: null- Neonatal Jaundice
Conditions
Interventions
Intervention1: Intermittent phototherapy: Intermittent phototherapy with 1 hour on and 2 hours off phototherapy with either LED or CFL light with matched flux recording. Duration will be till babies b
Sponsors
Sasi Bhushan Gottimukkala
Eligibility
Inclusion criteria
Inclusion criteria: Intermittent vs Continuous Phototherapy
Exclusion criteria
Exclusion criteria: Neonates with bilirubin in the exchange transfusion range, as per AAP charts Significant haemolytic jaundice (One or more of the following Low haemoglobin for gestational age Direct antibody test positive Rh incompatilibility setting with antenatal investigations showing evidence of isoimmunisation like Indirect antibody test positive, elevated middle cerebral peak systolic velocity in fetal Doppler USG, presence of hepatosplenomegaly and hydrops in foetal ultrasound) Already received > 5 hours of phototherapy Neonates with major congenital anomalies Neonates with birth asphyxia Significant hemodynamic instability Neonates with significant conjugated hyperbilirubinemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectiveness of Phototherapy -Rate of fall of Bilirubin -Duration of PhototherapyTimepoint: At baseline, then after every 12 hours till babies bilirubin values come down 2 mg/dl below the cutoff according to AAP chart for phototherapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Parental Satisfaction Serum NO levels Serum calcium Vitamin D levels Temperature Skin rashes DNA breakage analysisTimepoint: At Baseline and at discharge i.e. when babies bilirubin values come down 2 mg/dl below the cutoff according to AAP chart for phototherapy. | — |
Countries
India
Contacts
Public ContactDr Giridhar Sethuraman
Chettinad Hospital and Research Institute
Outcome results
None listed