Health Condition 1: null- babies admitted to NICU, fit for discharge
Conditions
Interventions
None listed
Sponsors
kerala institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. All preterm neonates admitted within 1 week of life in Neonatal intensive care unit during the study period. 2. Term neonates admitted within 1 week of life with any one of the following risk factors will be included in the study. a. Neonatal encephalopathy b. Culture proven sepsis (Blood/Urine/CSF) /clinical sepsis (CRP > 15 mg / L) c. Severe hyperbilirubinemia (Total serum bilirubin >20mg/dl) d. Symptomatic hypoglycaemia e. Neonates with shock requiring inotropes f. All other neonates who warrant follow-up as they develop increased risk of NDD.
Exclusion criteria
Exclusion criteria: 1. Proven intra uterine infection 2. Major congenital malformations requiring surgery 3. Proven Inborn error of metabolism 4. Proven genetic condition in the neonate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of Hammersmith Neonatal Neurological Examination at discharge to predict neurodevelopmental disabilityTimepoint: 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare accuracy of following tools in predicting NDD at 1 year a) HNNE vs neuro imaging b) HNNE vs serial head circumference c) HNNE vs perinatal risk factors 2. To compare performance of HNNE in preterm neonates at discharge (35 weeks â?? 39 weeks PMA) vs HNNE at estimated term gestational age (40 weeks PMA) 3. Inter observer reliability and time required to perform HNNE Timepoint: 1 year | — |
Countries
India
Contacts
Public ContactNaveen Jain
Kerala Institute of Medical Sciences
Outcome results
None listed