FindTrial
Sign In

The Role of carbon dioxide (CO2) gap between artery and vein in septic shock patients

Central venous-to-arterial carbon dioxide difference: a tool in resuscitation of patients with sepsis and septic shock.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/12/011029
Enrollment
100
Registered
2017-12-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients with sepsis and septic shock

Interventions

None listed

Sponsors

CARE Hospitals
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Admission to medical high dependency unit or general ICU. 2)All patients admitted to medical high dependency unit or general ICU who have central venous line (subclavian or Internal Jugular veins) and an arterial line are included in this study.

Exclusion criteria

Exclusion criteria: 1) less than 18 yrs old or pregnant, 2) Hepatitis B/C are present, 3) Neutropenia due to causes other than sepsis,

Design outcomes

Primary

MeasureTime frame
The goal is to enroll patients prior to resuscitate and ultimately, those patients who do develop high â??PCO2gap will form the study group and those patients who have low â??PCO2gap will serve as the controls.Timepoint: 24 hours—

Secondary

MeasureTime frame
Mortality rates with high â??PCO2 will be comparable with the other mortality predicting models like APACHE II.Timepoint: within 24 hours of ICU admission—

Countries

India

Contacts

Public ContactDr K Venkat Raman

CARE HOSPITALS

dr.venkatraman.kola@carehospitals.com040-30418888

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026