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Evaluation of the role of Dexmedetomidine in reducing pain after surgery for brain tumors.

Effect of Dexmedetomidine as an adjuvant to Bupivacaine for scalp blocks in supratentorial craniotomy.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/12/011024
Enrollment
50
Registered
2017-12-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Consenting, non pregnant, non lactating adult patients coming for supratentorial craniotomy

Interventions

Intervention1: Dexmedetomidine: Intervention group to receive scalp block with a solution containing Bupivacaine, with Dexmedetomidine added as an adjuvant. The control group to receive scalp block wi
Supratrochlear, Supraorbital, Zygomaticotemporal, Auriculotemporal, Great auricular, Lesser occipital and Greater occipital nerves, will be given following indutcion of anesthesia.

Sponsors

Sree Chitra Tirunal Institute for Medical Sciences and Technology
Lead Sponsor
Dr Gautham N S
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Consenting, non pregnant, non lactating adult patients coming for supratentorial craniotomy will participate in the study. Minors, neonates, persons incompetent to give informed consent, prisoners, normal/healthy volunteer, student, staff of the institute are not planned to be included in the study.

Exclusion criteria

Exclusion criteria: Previous craniotomy,Hypertensive patients, Diabetics, Pre-operative GCS

Design outcomes

Primary

MeasureTime frame
Duration of post-operative analgesia, defined as the time when the Visual Analog Score is greater than or equal to 4 in the post operative periodTimepoint: Visual Analog Score to be assessed post operatively at 1 hour, 2 hours, 4 hours, 6 hours, 8 hours, 10 hours, 12 hours, 16 hours and 24 hours.

Secondary

MeasureTime frame
Intra-operative anaesthetic requirement; Number of additional doses of Fentanyl required to ensure adequate intraoperative analgesiaTimepoint: At the end of surgery;Post operative sedation score; Ramsay Sedation ScaleTimepoint: Every hour for 6 hours post operatively;Post-operative analgesiaTimepoint: VAS score

Countries

India

Contacts

Public ContactDr Ajay Prasad Hrishi P

Sree Chitra Tirunal Institute for Medical Sciences and Technology

drajay@sctimst.ac.in9495239765

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026