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Influence of genes on ayurvedic treatment in Amavata (rheumatoid arthritis)

Influence of single nucleotide polymorphisms in the treatment outcome of ayurvedic combination of simhanada guggulu in amavata with special reference to Rheumatoid arthritis

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/12/011022
Enrollment
100
Registered
2017-12-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Diagnosed Amavata and duration diseases is 1 - 9 years

Interventions

Intervention1: Simhanada Guggulu: Simhanada Guggulu is well known ayurvedic prescription mentioned in classics Bhaishajya Rathnavali Control Intervention1: No: There is no comparator agent used

Sponsors

Rajive Gandhi University of Health Sciences Karnataka
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Here patients included are diagnosed with Amavata and duration of disease is 5±4 years.Diagnosis of amavata would be on the basis of Ayurvedic principles of Madhava Nidanam of Madhavakara.Patients diagnosed with Amavata would to be subjected to undergo clinical examination by an allopathic doctor in SDM hospital in Udupi for the diagnosis of RA based on 1987 American College of Rheumatology criteria

Exclusion criteria

Exclusion criteria: Patients are not diagnosed amavata as per ayuvedic principles and rheumatoid arthritis. Individuals of below and above the age. Patients suffering from other systemic disorders like tuberculosis, SLE.

Design outcomes

Primary

MeasureTime frame
The SNPs that influence drug response forms the personalised medicine and these differences could be helpful in the understanding the drug reactions.Ayurgenomics is the integration of the principles of Ayurveda with genomics. The primary challenge of Ayurgenomics is to establish the correlation between DNA and â??Prakritiâ??. Therefore Ayurgenomics has the potential to be a platform to achieve personalized drug therapy.Timepoint: 90 days

Secondary

MeasureTime frame
SNPs, Prakriti and treatment outcome of ayurvedic drug will be establishedTimepoint: 60-70%

Countries

India

Contacts

Public ContactDr Veerakumar

SDM college of Ayurveda and Hospital

khadiravana@gmail.com9743490753

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026