The Effect of Probiotic VSL#3 and Lifestyle Intervention in Obese Children with Non-Alcoholic Fatty Liver Disease (NAFLD)

The Effect of Probiotic VSL#3 and Lifestyle Intervention in Obese Children with Non Alcoholic Fatty Liver Disease(NAFLD):A Randomized Clinical Trial - NA

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/12/010997

Enrollment

100

Registered

2017-12-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: VSL#3 probiotic live freeze dried lactic acid bacteria and bifidobacteria capsules: 4 capsules of VSL#3 probiotic less than 10yrs and 8 capsules above 10 yrs for 4 months Control Inter

Eligibility

Inclusion criteria

Inclusion criteria: Obese children in age group of 5-18 years old with NAFLD (BMI) >=95th or 85th to 94th percentile with risk factors

Exclusion criteria

Exclusion criteria: Presence of liver disease due to hypothyroidism, wilson disease, viral hepatitis, cystic fibrosis, celiac disease, autoimmune hepatitis, drugs induced steatosis and gastrointestinal abnormalities.

Design outcomes

Primary

Measure	Time frame
The primary outcome is the evaluation of beneficial effect of probiotic VSl#3 for the treatment of fatty liver disease in obese childrenTimepoint: 4 months intervention	—

Secondary

Measure	Time frame
Assessment of Probiotic VSL#3 for controlling the biochemical parameters LFT Lipid profile etc Hunger hormone leptin ghrelinTimepoint: 4 months intervention	—

Countries

India

Contacts

Public ContactPooja Goyal

Lovely Professional University Phagwara Punjab

pooja_goyal9@yahoo.com9872033173

Outcome results