Effect of Yoga in patients with Vasovagal Syncope

Effect of Yoga on Clinical Outcomes and Quality of Life in patients with Vasovagal Syncope. A randomized controlled trial - LIVE-Yoga

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/12/010917

Enrollment

100

Registered

2017-12-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R55- Syncope and collapse

Interventions

Intervention1: Yoga: Patients will be given Yoga as an intervention along with the standard medical therapy. The yoga intervention comprises of physical postures, pranayama (controlled breathing), and

Eligibility

Inclusion criteria

Inclusion criteria: 1. All adults between 15-70 years of age 2. Both genders 3. Diagnosed to have VVS (HUTT positive within last 3 months) 4. At least two episode of syncope or pre-syncope event in the last 3 months prior to enrolment 5. Patients with no other cause of Syncope 6. Patients willing and able to practice Yoga at least for 40 minutes /5 days/week

Exclusion criteria

Exclusion criteria: 1. Not willing or not fulfilling the criteria of inclusion 2. Practicing yoga before 3. Accelerated hypertension( > 180/110 mm Hg) 4. Any disease which is potent to cause syncope like significant arrhythmias (Atrial Fibrillation, Atrial Flutter, Ectopic Atrial Tachycardia), Mobitz Type 2, Complete Heart Block, Sinus Bradycardia(Pause > 3 sec), Sick Sinus Syndrome with AF(pause > 5 sec in awake state), Heart Failure(LVEF = 35 %, > NYHA-II)

Design outcomes

Primary

Measure	Time frame
To evaluate the effect of Yoga on the clinical outcome (Number of episodes of syncope and presyncope ) of patients with VVS over a follow-up period of one year.Timepoint: Baseline, 6 weeks, 6 months, 12 months	—

Secondary

Measure	Time frame
To evaluate the effect of Yoga on the Quality of Life(QoL) in patients with Vasovagal Syncope. Timepoint: Baseline, 6 weeks, 6 months, 12 months;To evaluate the short-term effect of yoga in HUTT positive response in patients with Vasovagal Syncope.Timepoint: Baseline, 6 weeks;To evaluate the effect of Yoga on Autonomic function in patients with Vasovagal Syncope.Timepoint: Baseline, 6 weeks;Adherence of yoga practice of the patients with Vasovagal Syncope.Timepoint: Baseline, 6 weeks, 6 months, 12 months	—

Measure

Time frame

To evaluate the effect of Yoga on the Quality of Life(QoL) in patients with Vasovagal Syncope. Timepoint: Baseline, 6 weeks, 6 months, 12 months;To evaluate the short-term effect of yoga in HUTT positive response in patients with Vasovagal Syncope.Timepoint: Baseline, 6 weeks;To evaluate the effect of Yoga on Autonomic function in patients with Vasovagal Syncope.Timepoint: Baseline, 6 weeks;Adherence of yoga practice of the patients with Vasovagal Syncope.Timepoint: Baseline, 6 weeks, 6 months, 12 months

—

Countries

India

Contacts

Public ContactDr Gautam Sharma

All India Institute of Medical Sciences, New Delhi

drgautamsharma12@gmail.com01126549326

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026