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Changes in lung function after total injectable anaesthesia and balanced anaesthesia with desflurane

A prospective randomized study to evaluate and compare changes in lung function parameters after total intravenous anaesthesia and balanced anaesthesia with desflurane

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/12/010910
Enrollment
60
Registered
2017-12-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ï?· ASA physical status I and II. ï?· Patients in the age-group 18-60 years undergoing mastoid surgery.

Interventions

Intervention1: effect of total intravenous anaesthesia on postoperative pulmonary fuunction test: Anaesthesia was induced with intravenous propofol 1.5â??3mg/kg and propofol infusion was commenced at

Sponsors

Department of Anesthesiology and Intensive Care Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA physical status I and II. 2. Patients in the age-group 18-60 years undergoing mastoid surgery.

Exclusion criteria

Exclusion criteria: 1. BMI > 30 kg/m2 2. History of smoking 3. Cardiopulmonary disease 4. Obstructive sleep apnoea syndrome 5. Pregnancy 6. Kypho-scoliosis 7. Neuromuscular disorder. 8. Patients who were uncooperative, unable to perform spirometry or mentally retarded.

Design outcomes

Primary

MeasureTime frame
change in forced expiratory volume in first second (FEV1)Timepoint: 1, 3 and 24 hours postoperatively

Secondary

MeasureTime frame
Secondary outcome measures were changes in peak expiratory flow rate (PEFR), forced vital capacity (FVC), mid expiratory flow rate at 25 to 75% of vital capacity manoeuvre (MEF 25-75) and peripheral oxygen saturation (SpO2)Timepoint: 1, 3 and 24 hours postoperatively

Countries

India

Contacts

Public ContactSAURABH SHARMA

Maulana Azad Medical College and associated LN Hospital

raktima.anand@gmail.com8921816041

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026