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Comparison of Interleukin-35 in gum sulcus fluid in diseases of the gums before and after cleaning of teeth.

Comparative evaluation of gingival crevicular fluid interleukin- 35 concentrationin gingivitis and chronic periodontitis subjects before and after non-surgical periodontal therapy.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/12/010905
Enrollment
80
Registered
2017-12-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Gingivitis, Chronic periodontitis

Interventions

Control Intervention1: Nil: Nil

Sponsors

The Oxford dental college and hospital Bangalore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Individuals aged 20-30 years for group I (Gingivitis group). 2. Individuals aged 30-50 years for group II (Chronic periodontitis group). 3. Periodontally healthy subjects with atleast 20 teeth with no attachment loss and probing depth 4. Subjects diagnosed with chronic periodontitis (Probing pocket depth>=5 mm and loss of clinical attachment >=3mm). 5. Subjects who have not received periodontal therapy, within preceding six months.

Exclusion criteria

Exclusion criteria: 1. Patients with history of systemic diseases that could affect the periodontium. 2. Smokers. 3. Patients on immunosuppressive agents. 4. Pregnant and lactating women. 5. Subjects who have received any anti-inflammatory drugs and antibiotics in the previous six months. 6. Diseases of oral hard and soft tissues except caries and periodontal disease. 7. Patients on orthodontic appliances and oral mucosal inflammatory condition.

Design outcomes

Primary

MeasureTime frame
Evaluation of concentration of Interleukin-35 in GCF before and after scaling and root planingTimepoint: at baseline and 3 months following scaling and root planing—

Secondary

MeasureTime frame
Plaque Index(Sillness J and Loe H 1964) Gingival Index(Loe H and Sillness 1963) Probing Pocket Depth. Bleeding On Probing Clinical Attachment Level. Modified sulcus bleeding index Timepoint: at baseline and 3 months following scaling and root planing—

Countries

India

Contacts

Public ContactDr Sarika Jain

The Oxford dental college and hospital, Bangalore

drsushmadas@yahoo.co.in9986726021

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026