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The use of short acting local anaesthetic with and without an opioid for short duration surgeries under spinal anaesthesia.

A comparative study of 2-chloroprocaine vs 2- chloroprocaine with buprenorphine for spinal anaesthesia in short duration surgeries

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/12/010900
Enrollment
90
Registered
2017-12-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients undergoing lower abdomen and lower limb elective surgeries of less than 60 minutes duration.

Interventions

Intervention1: Group C: Inj2-chloroprocaine 1% 40mg (4 ml) will be used for spinal anaesthesia Control Intervention1: Group B: Inj2-chloroprocaine 1% 40mg (4 ml) with 60 micrograms of buprenorphine wi

Sponsors

Ramaiah Medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients Aged between 18-65 years of either sex 2 American Society of Anesthesiologists (ASA) Grade I and II for elective surgeries under spinal anaesthesia 3 Surgeries lasting less than 60 minutes

Exclusion criteria

Exclusion criteria: 1 Patients who refuse to give consent to spinal anaesthesia 2 Patients who have absolute or relative contraindications to spinal anaesthesia 3 Pregnant patients 4 Allergy to test drugs

Design outcomes

Primary

MeasureTime frame
To assess the time to onset, duration of anaesthesia, two segment regression, complete regression of spinal anaesthesia and time for first post operative analgesic requirement in 2-chloroprocaine and 2-chloroprocaine with buprenorphine groups. Timepoint: An independent blinded assessor will evaluate the sensory and motor blocks every three minutes for 15 min, then every 15 min until the complete regression of motor block.

Secondary

MeasureTime frame
Pulse, blood pressure, oxygen saturation and any adverse eventsTimepoint: 3, 6, 9 12, 15, 30,45, 60, 75, 90, 115 minutes

Countries

India

Contacts

Public ContactDr Vinayak P S

Ramaiah Medical College

vinayakps@msrmc.ac.in9900859460

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026