Health Condition 1: null- Drug resistant epilepsy
Conditions
Interventions
Intervention1: Modified Atkins Diet: In the modified Atkins diet, patients limit their daily intake of net carbohydrates to 10â??20 g/day
Control Intervention1: Low Glycemic Index Diet: In Low glycemi
Sponsors
Jaya Shankar Kaushik
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 6 months to 5 years with drug resistant epilepsy (failure of adequate trials of two tolerated, appropriately chosen and used antiepileptic drug schedules (whether as monotherapies or in combination) to achieve sustained seizure freedom)
Exclusion criteria
Exclusion criteria: (i) Children with known or suspected inborn error of metabolism. (ii) Children with renal, pulmonary, cardiac or hepatic dysfunction. (iii) Severe malnutrition (weight for length and height for age less than 3 SD for mean as per WHO growth charts), (iv) Children from families who lack motivation will also be excluded as it might affect the compliance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of children who achieved seizure freedom as per parental reports at 4 weeks and 12 weeks in both the groupsTimepoint: 4 weeks 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Description and proportion of adverse effect of diet as reported by parentsTimepoint: four and twelve weeks;proportion of children who achieved more than fifty percent reduction in seizure as per parental reportTimepoint: four and twelve weeks;Proportion of children who achieved more than ninty percent reduction in seizure as per parental reportTimepoint: four and twelve weeks | — |
Countries
India
Contacts
Public ContactSurbhi Gupta
Pt B D Sharma PGIMS Rohtak
Outcome results
None listed