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To assess the results of medicine made from patients extracted blood with/without medicine made from bone for preserving tooth socket after extraction- a randomized control trial

To evaluate efficacy of APRF Plus with/without Osseous bone graft in socket preservation and ridge augmentation â?? A randomized control trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/12/010879
Enrollment
20
Registered
2017-12-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Need of extraction in upper batch ( from incisor to premolar)

Interventions

Intervention1: Advanced Platelet rich fibrin (APRF Plus) mixed with Osseous bone graft (Sybograf Plus): 20 ml blood will be withdrawn from the patients body (under sterile conditions) to make Platelet

Sponsors

Manipal College of Dental Sciences Manipal
Lead Sponsor
Dr Manasi Yewale
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients above 20 years of age who are systemically healthy in need of extraction from incisor to premolar in maxilla (Upper jaw) and willing for implant placement will be included

Exclusion criteria

Exclusion criteria: Patients who have abusive habits like smoking, women who are pregnant or lactating and any other systemic diseases or on anti-inflammatory or antibiotics drugs for past 6 months will be excluded

Design outcomes

Primary

MeasureTime frame
1.Mean width ridge difference between outer border of buccal and cortical plate at 1,3,5mm 2.Socket depth at 1,3,5 mm 3.Bone density Timepoint: recall after 1 week and 6 months

Secondary

MeasureTime frame
1,Mean width ridge difference between outer border of buccal and cortical plate at 1,3,5mm 2.Socket depth at 1,3,5 mm 3.Bone density Timepoint: recall after 6 months to assessfor implant placement

Countries

India

Contacts

Public ContactDr Manasi Yewale

Manipal college of Dental Sciences Manipal

subraya.bhat@manipal.edu9632170341

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 10, 2026