Health Condition 1: K801- Calculus of gallbladder with othercholecystitis Health Condition 2: null- Male and female patients between 18-60 years of age belonging to ASA physical status I and II scheduled for elective laparoscopic surgery
Conditions
Interventions
Intervention1: Test drug or normal saline will be administered 5 min after intubation: Test drug or normal saline will be administered 5 min after intubation and the hemodynamic variables will be moni
Sponsors
university college of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA I and II 2. Male or female 3. between 18-60 years undergoing elective laparoscopic surgery under general anaesthesia
Exclusion criteria
Exclusion criteria: 1. Patientâ??s refusal 2. History of allergy to opioids 3. History of uncontrolled cardiovascular conditions e.g. hypertension, ischemic heart disease, conduction defects etc. 4. Compromised renal/hepatic/ neuronal functions 5. Pregnant and lactating women 6. Endocrine disease e.g. hyper and hypothyroidism. 7. On any of the following drug e.g. calcium channel blockers, beta blockers, magnesium sulphate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure (MAP), Heart rate (HR), Systolic blood pressure (SBP), diastolic blood pressure (DBP) after creation of pneumoperitoneumTimepoint: 5 min after intubation, at the time of creation of pneumoperitoneum, 5, 10, 15, 30, 45, 60, 75, 90 min after pneumoperitoneum, at the time of deflation and after extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative haemodynamics, time to request of first rescue analgesic sedation side effects like nausea, vomiting.Timepoint: 0, 30, 60, 90, 120 min post-operative | — |
Countries
India
Contacts
Public ContactDr Meghna Singhal
university college of medical sciences,delhi
Outcome results
None listed