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To see the effect of giving dextrose (sugar) in vein for preventing vomiting in patients after operation of gall bladder removal

Perioperative dextrose infusion for prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/12/010799
Enrollment
255
Registered
2017-12-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Dextrose infusion: 5 percent and 10 percent dextrose infusion will be infused at time of gall bladder removal Control Intervention1: Normal saline: Normal saline will be infused at the

Sponsors

Safdarjung Hospital New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiologists Physical Status I and II adults 2. Either gender 3. Aged 18-65 years 4. Scheduled for elective laparoscopic cholecystectomy under general anaesthesia

Exclusion criteria

Exclusion criteria: 1. Patients with cardiovascular disease 2. Diabetes Mellitus 3. Jaundice, hepatic or renal disease 5. Pregnant females 6. Currently receiving opioids, steroid or antiemetic drugs 7. Increased intracranial tension 8. Cancer patients on chemotherapy or opioids 9. Abnormal blood glucose on the morning of surgery

Design outcomes

Primary

MeasureTime frame
To compare the incidence of post operative nausea and vomiting in patients receiving perioperative intravenous dextrose 5 percent, 10 percent or saline infusion in patients undergoing laparoscopic cholecystectomy under general anaesthesiaTimepoint: At 0, 30 min, 60 min, 90 min, 2 h, 6 h and 24 h after arrival in Post Anaesthesia Care Unit—

Secondary

MeasureTime frame
1. To compare the severity of postoperative nausea and vomiting (PONV), the requirement of rescue antiemetics in the three groups. 2. To determine the optimum dose of dextrose for prevention of PONV. 3. To compare intraoperative and patient characteristics in patients with and without PONV. Timepoint: At 0, 30 min, 60 min, 90 min, 2 h, 6 h and 24 h after arrival in Post Anaesthesia Care Unit—

Countries

India

Contacts

Public ContactSmita Prakash

Vardhmaan Mahavir Medical College and Safdarjung Hospital, New Delhi

drsunilprakash@gmail.com9810347125

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026