Health Condition 1: null- Tinea
Conditions
Interventions
Intervention1: 1. Terbinafine daily
2. Terbinafine daily with Fluconazole weekly
3. Terbinafine daily with Fluconazole daily
: 1. Terbinafine (6mg/kg/d)
2. Terbinafine (6mg/kg/d) with Fluconazole (12m
Sponsors
Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Tinea corporis/cruris/faciei 2. Positive KOH microscopy for fungus 3. Patient not on terbinafine or fluconazole 4. Patient on itraconazole but unsatisfied with treatment Criteria 1 to 3 mandatory, criteria 4 applies if patient on itraconazole
Exclusion criteria
Exclusion criteria: 1. Pregnancy 2. Lactation 3. Inability to come for follow up 4. History of adverse reaction to terbinafine or fluconazole 5. Current treatment with drugs with potential of interaction with terbinafine or fluconazole 6. Renal or liver or cardiac disease or history of chest pain 7. Abnormalities in CBC, LFT, RFT (for hemoglobin 100 units per liter considered exclusion criteria)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cure rate at different time points. Cure defined as 1. Complete clearance of lesions, and 2. Negative KOH microscopyTimepoint: 0, 2, 4, 6, 8 weeks. Post-cure follow up at 1 month | — |
Secondary
| Measure | Time frame |
|---|---|
| Relapse rateTimepoint: 1 month after cure | — |
Countries
India
Contacts
Public ContactPrakriti Shukla
Institute of Medical Sciences, Banaras Hindu University
Outcome results
None listed