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Comparison of 3 agents used in giving anaesthetia in children undergoing cardiac surgeries in term of heart function using a specific echo cardiology parameter

â??Comparison of effects of induction agents ketamine, etomidate and sevoflurane on left ventricular strain and strain rate in pediatric patients underging cardiac surgeriesâ??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/12/010764
Enrollment
90
Registered
2017-12-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients posted for elective cardiac surgeries

Interventions

Intervention1: ketamine: pencyclidine derivative induction agent , 2 mg / kg intravenous single dose for anaesthetia induction Control Intervention1: sevoflurane: inhalational agent of choice for ind

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Elective cardiac surgeries co-operative patients Patients with good window for trans thoracic echocardiograhy

Exclusion criteria

Exclusion criteria: a) Severe left ventricular dysfunction (EF b) Low cardiac output syndrome c) Severe pulmonary hypertension d) On vasoactive infusions e) Patients in heart failure f) Redo / Emergency surgeries g) Patients on mechanical ventilation

Design outcomes

Secondary

MeasureTime frame
hemodynamic parameters- heart rate , systolic bllod pressure, diastolic bood pressure, mean arterial pressureTimepoint: T0-baseline T1-1 minute after drug administration T2-2 minutes after intubation—

Primary

MeasureTime frame
1) Left ventricular strain 2) Left ventricular strain rate Timepoint: T0-baseline T1-1 minute after drug administration T2-2 minutes after intubation—

Countries

India

Contacts

Public ContactMinati Choudhury

AIIMS

nanditha.iyengar88@gmail.com7358178544

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026