A clinical trial to study the effect of an absorbable gel containing Mango leaf extract for treatment of Chronic Periodontitis

THE EFFICACY OF MANGIFERIN GEL AS CONTROLLED RELEASE LOCAL DRUG DELIVERY SYSTEM IN THE TREATMENT OF CHRONIC PERIODONTITIS.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/12/010747

Enrollment

Registered

2017-12-04

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Chronic Generalised Periodontitis

Interventions

Intervention1: Mangiferin gel: Mangiferin extract in Chitosan base in gel form 2ml delivered into diseased site (periodontal pocket) with a blunt tuberculin syringe once Control Intervention1: Scaling

Eligibility

Inclusion criteria

Inclusion criteria: Patients with localized periodontal pockets in maxillary or mandibular arch with pocket depth more than and equal to 5mm Presence of minimum 20 natural teeth

Exclusion criteria

Exclusion criteria: Patients with history of any systemic disease and conditions. Patients having received antibiotics or periodontal treatment in the past 6 months. Patients with known history of allergy to mango Smokers. Pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
Reduction in Probing attachment level reduction in Clinical attachment lossTimepoint: At 3 months from local drug delivery	—

Secondary

Measure	Time frame
Release of Mangiferin in GCF release of Mangiferin in salivaTimepoint: 3 months	—

Countries

India

Contacts

Public ContactDr Remya Warrier

Manipal College of Dental Sciences, Manipal

kmbhatcods@yahoo.co.in7406610129

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026