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Effect of gum treatment on a acute phase protein and iron indices in periodontitis patients undergoing haemodialysis

Effect of nonsurgical periodontal therapy on C-reactive protein and iron indices in haemodialysis patients with chronic periodontitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/12/010727
Enrollment
60
Registered
2017-12-01
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease Health Condition 2: null- Group I - Chronic Periodontitis under hemodialysis for less than a year Group II - Chronic Periodontitis under hemodialysis for more than a year Group III - Chronic Periodontitis

Interventions

Intervention1: Patients with Chronic Periodontitis and under hemodialysis for Less than a year: Scaling will be done using ultrasonic instruments and root planing will be done with Gracey Curettes Ed

Sponsors

Sheethel Menon V
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: A. Group I: Renal patients undergoing haemodialysis for less than a year with chronic periodontitis i. Patients with Chronic periodontitis will be diagnosed when there is attachment loss �5mm in more than 30% of teeth (according to the criteria of 1999 American Academy of Periodontology Workshop). ii. Patients with more than or equal to 20 teeth iii. Patients with clinical bleeding on probing. iv. Patients undergoing haemodialysis for atleast 3months and less than a year. B. Group II: 20 renal patients undergoing haemodialysis for more than a year with chronic periodontitis i. Patients with Chronic periodontitis will be diagnosed when there is attachment loss �5mm in more than 30% of teeth (according to the criteria of 1999 American Academy of Periodontology Workshop). ii. Patients with more than or equal to 20 teeth iii. Patients with clinical bleeding on probing. iv. Patients undergoing haemodialysis for more than a year. C. Group III: 20 systemically healthy periodontitis patients i. Patients with Chronic periodontitis will be diagnosed when there is attachment loss �5mm in more than 30% of teeth (according to the criteria of 1999 American Academy of Periodontology Workshop). ii. Patients with more than or equal to 20 teeth iii.Patients with clinical bleeding on probing.

Exclusion criteria

Exclusion criteria: 1.Individuals with uncontrolled hypertension inspite of medication 2.Edentulous patients 3.Smokers, alcoholics, pregnant women and lactating mothers. 4.Patients needing prophylactic antibiotic medication in association with periodontal probing. 5.Patients who had undergone periodontal treatment in the past 6 months

Design outcomes

Primary

MeasureTime frame
1) C reactive protein level 2) Iron Indices - Serum Iron, Serum Ferritin, Total Iron binding capacityTimepoint: 1 month

Secondary

MeasureTime frame
1) Plaque index 2) Gingival Index 3) Probing pocket depth 4) Clinical Attachment levelTimepoint: 1 month

Countries

India

Contacts

Public ContactArun Sadasivan

Sree Mookambika Institute of Dental Sciences

sadasivan_arun@hotmail.com9847246961

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026