Health Condition 1: null- bronchiolitis
Conditions
Interventions
Intervention1: adrenaline and dexamethasone combination: adrenaline nebulisation 5 ml 6 hourly till discharge & single intramuscular dexamethasone 0.6 mg/kg dose on admission
Control Intervention1: ad
Sponsors
Department of Pediatrics
Eligibility
Inclusion criteria
Inclusion criteria: • All cases of bronchiolitis with a Respiratory Distress Assessment Instrument (RDAI) score of 4 to 15 [on a scale of 0 (mild) to 17 (severe)] • An RDAI score involves assigning a numerical value to 6 separate assessments; the sum of these scores provides an RDAI score ranging from 0 to 17, with increasing scores indicating increasing respiratory distress.
Exclusion criteria
Exclusion criteria: 1. Who received oral or inhaled corticosteroids during the preceding 2 weeks. 2. Previous diagnosis of asthma or Wheeze Associated Lower Respiratory Tract Infection. 3. Chronic disease that may affect cardiopulmonary status of the patient, such as • Bronco pulmonary dysplasia • Cystic fibrosis • Congenital heart disease • Immune deficiency. 4. Who are preterm with corrected age of less than 4 weeks at presentation 5. Congenital malformation of respiratory and cardiovascular system 6. Severe disease [clinical score > 15] requiring mechanical ventilation: a. Saturation b. Obtunded consciousness, and/or c. Progressive respiratory failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| reduction in severity of symptomsTimepoint: 24 hours of starting drug treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| reduction in duration of hospitalisationTimepoint: 8 days | — |
Countries
India
Contacts
Public ContactDr Jayendra Gohil
Sir T. Hospital, Government Medical College
Outcome results
None listed