Skip to content

Effect of scaling and rool planing on Plasma Osteoprotegerin Levels in patients with and without diabetes mellitus

Effect of Non-Surgical Periodontal Therapy on Plasma Osteoprotegerin Levels in Chronic Periodontitis patients with and without controlled Type II Diabetes Mellitus

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/11/010652
Enrollment
40
Registered
2017-11-27
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Subjects with Chronic periodontitis (20 nos) and subjects having Chronic Periodontitis with Type II diabetes Mellitus (20 nos) Health Condition 2: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Effect of Non-Surgical Periodontal Therapy on Plasma Osteoprotegerin Levels in Chronic Periodontitis patients with and without controlled Type II Diabetes Mellitus: Patients will be div

Sponsors

Sheethel Menon V
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Chronic periodontitis will be diagnosed when there is attachment loss �5mm in more than 30% of teeth Patients with more than or equal to 20 teeth Patients with clinical bleeding on probing. Patients were considered to be diabetic when presenting with fasting glucose levels in excess of 126mg/dL and glycated hemoglobin above 6.5%

Exclusion criteria

Exclusion criteria: Patients suffering from any systemic condition(except type IIdiabetes) that could affect the periodontal disease (immunological disorders) and affect the level of Plasma Osteoprotegerin levels. Smokers, alcoholics, pregnant women and lactating mothers. Patients needing prophylactic antibiotic medication in association with periodontal probing. Patients who used antibiotics or periodontal treatment in the past 6 months.

Design outcomes

Primary

MeasureTime frame
Increase in Plasma Osteoprotegerin LevelTimepoint: 3-4 weeks

Secondary

MeasureTime frame
Reduction in progression of Chronic PeriodontitisTimepoint: 1 month

Countries

India

Contacts

Public ContactSheethel Menon V

Sree Mookambika Institute of Dental Sciences

sheethel.menon@gmail.com9947020908

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026