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Comparison of medical vs early surgical treatment in spinal tuberculosis

Comparison of medical vs early surgical treatment in spinal tuberculosis and outcome assessment: A randomized study.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/11/010596
Enrollment
81
Registered
2017-11-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Tuberculosis spine patients on anti tubercular drugs

Interventions

Intervention1: Medical Treatment: Anti Tubercular Drugs Intervention2: Surgical Treatment: Surgical procedures + Anti tubercular drugs Control Intervention1: medical treatment: Anti tubercular drugs

Sponsors

King George s Medical University Lucknow UP
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 All recent ( 2 Radiological features of central spinal canal narrowing (Anterior-posterior diameter or Area) of 25-50% (in cervical and thoracic region) and 50-75% (in lumbar region).

Exclusion criteria

Exclusion criteria: 1 Patient already taking ATT for more than 1 month 2 Patients with other medical illness disease such as uncontrolled diabetes, uremia, hepatic failure 3 Human immunodeficiency virus disease 4 Multiple non contagious vertebral involvement 5 Patients/ attendants refusing consent 6. Absolute surgical criteria • Central spinal canal narrowing > 50% (in cervical and thoracic region) and >50-75% (in lumbar region). • Greater than 2 vertebral collapse with or without spinal canal narrowing. • Clinical deterioration of 2 or more power grade with features of compression.

Design outcomes

Primary

MeasureTime frame
Modified Barthel index Modified Japenese Orthopaedic Association ScoreTimepoint: Modified Barthel index Modified Japenese Orthopaedic Association Score at 1,3,6,12 months

Secondary

MeasureTime frame
Duration of anti tubercular treatment Timepoint: Duration of anti tubercular treatment6,12,18,24 months

Countries

India

Contacts

Public ContactSomil Jaiswal

King George s Medical University

dr.somil26@gmail.com7755075630

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026