Health Condition 1: null- Chronic periodontitis
Conditions
Interventions
Intervention1: Curcumin incorporated mucoadhesive patch: fabrication of mucoadhesive film will be done in the Department of Pharmaceutics, J.S.S College of Pharmacy, Mysuru
Control Intervention1: Plac
Sponsors
Anu Anil
Eligibility
Inclusion criteria
Inclusion criteria: 1. Systemically healthy patients 2. Bilateral moderate or advanced periodontitis in at least one arch which required periodontal surgery as confirmed by radiographs. 3. Previous history of treatment in both quadrants must be similar and the type and extent of surgical therapy indicated must be the same on both sides 4. minimum of 20 teeth 5. periodontal probing depth (PPD) equal to or greater than 5mm. 6. Consenting patients who are co-operative and able to come for regular follow up
Exclusion criteria
Exclusion criteria: 1. Pregnant /lactating women 2. Patients on antibiotic or NSAIDs therapy in the previous six months. 3. Patients who have undertaken any periodontal therapy in past 6 months 4. Smokers 5. Patients who are medically compromised or under therapeutic regimen that may alter the probability of tissue healing. 6. Patients who are known or suspected to be allergic to curcumin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect of a curcumin based mucoadhesive film on the post-operative inflammation after periodontal surgery.Timepoint: 1 hour 2 hours 3 hours 4 hours 5 hours 24 hours 48 hours 1 week 2 weeks 3 weeks 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| to assess clinical parameters visual analog scale and wound healing indexTimepoint: 1 hour 2 hours 3 hours 4 hours 5 hours 24 hours 48 hours 1 week 2 weeks 3 weeks 4 weeks | — |
Countries
India
Contacts
Public ContactAnu Anil
JSS Dental College and Hospital
Outcome results
None listed