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Amount of desflurane used at three different flow rates

Comparison of efficacy and evaluation of the optimal flow rate for desflurane anaesthesia at three different settings

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2017/11/010546
Enrollment
150
Registered
2017-11-17
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA Grade I and 2, non pregnant patients, of both sexes, in the age group of 18 to 70 years, consenting for general anaesthesia for laprascopic surgery lasting for 30 minutes to 3 hours

Interventions

Intervention1: Desflurane at 1 litres of flow rate for maintenance of general anaesthesia: General anaesthesia would be maintained by titrating desflurane at a flow rate of 1 litres to maintain an ent

Sponsors

Dr L H Hiranandani Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA 1 and 2 patients undergoing General anaesthesia for laprascopic abdominal and pelvic surgeries 2. Surgeries lasting approximately 30 minutes to 180 minutes 3. Patients giving valid consent 4. Age:18 to 70 year

Exclusion criteria

Exclusion criteria: •Patient refusal •ASA grade >2 •Chronic alcoholics/ smokers, acute alcohol intoxication •Pregnant women •Patients with neuromuscular diseases •Suspected Malignant hyperthermia •Persons with epidural analgesia catheter

Design outcomes

Primary

MeasureTime frame
Efficacy of desflurane with respect to maintenance haemodynamic parameters and depth of anaesthesiaTimepoint: At all time points intraoperatively after starting desflurane to switching off desflurane

Secondary

MeasureTime frame
1. Safety of low flow rates assessed by oxygenation of the patient 2. Incidence of awareness under anaesthesia 3. Consumption of desflurane 4. Recovery parameters of the patient after stopping desflurane like time for extubation, time for response to oral commands and time taken for eye openingTimepoint: 1. Throughout intraoperatively 2. Post operatively in the recovery room and after 24 hours 3. After stopping desflurane 4. After stopping desflurane

Countries

India

Contacts

Public ContactDr Meenoti Potdar

Dr. Lakhumal Hiranand Hiranandani Hospital

meenoti@yahoo.com9920627839

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026