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Effect of oxygen on management of patients having brain surgery

â??Effect of different inhaled oxygen concentration on PaCO2-EtCO2 gradient in neurosurgical patients. â??

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2017/11/010499
Enrollment
40
Registered
2017-11-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- neurosurgical patients Health Condition 2: G952- Other and unspecified cord compression

Interventions

None listed

Sponsors

Dr Hemangi S karnik
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients undergoing neurosurgical procedures in supine or supine with head up position. 2) Patients needing invasive arterial access during surgery.

Exclusion criteria

Exclusion criteria: 1) Patients with impaired pulmonary gas exchange (baseline hypercarbia,hypoxia). 2) Patients with dependence on oxygen supplementation or CPAP. 3) Patients with bronchial asthma/COPD. 4) Patients with chest trauma/ chest drain in situ. 5) Operated pneumonectomy or lobectomy in past. 6) Patients with abdominal distension /pregnancy/ascites/any other cause affecting breathing. 7) Any contraindication for nitrous oxide. 8) Patients requiring frequent changes in ventilatory strategies.

Design outcomes

Primary

MeasureTime frame
To ascertain if PaCO2_EtCO2 gradient changes with varying FiO2 concentration.Timepoint: August 2017—

Secondary

MeasureTime frame
to find correlation between FiO2 % and PaCO2-EtCO2 gradient,if any.Timepoint: June 2017—

Countries

India

Contacts

Public ContactDr Hemangi S Karnik

LTMMC,sion.Mumbai

dr_hemangi@hotmail.com9324501900

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026