Health Condition 1: K80-K87- Disorders of gallbladder, biliary tract and pancreas Health Condition 2: null- Patient with Acute pancreatitis having acute fluid collection presenting in less than 14 days of onset of pancreatitis
Conditions
Interventions
Intervention1: Group 1- Early drainage: In this group, patients will undergo percutaneous pigtail drainage within 2-3 days of suspected infected acute fluid collection during the second or third wee
Sponsors
No sponsor
Eligibility
Inclusion criteria
Inclusion criteria: (i) Patients with acute pancreatitis diagnosed as per revised Atlanta classification (ii) Hospitalisation within 14 days of onset of pancreatitis (iii) Patient suspected to have infected acute fluid collection (iv) Providing consent for study
Exclusion criteria
Exclusion criteria: (i) Age 75 years (ii) Patients with systemic organ dysfunction in the form of altered sensorium and/or hypotension requiring inotropic support and/or respiratory failure requiring mechanical ventilation and/or acute kidney injury requiring hemodialysis at the time of enrolment in the study. (iii) Other major co-morbid conditions e.g. Acute myocardial infarction, major gastrointestinal bleeding, chronic kidney disease, cirrhosis of the liver, human immunodeficiency virus (HIV) infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite Primary Outcome: (i) New organ failure or deterioration in existing organ failure (ii) Need for necrosectomy due to failure to control sepsis (iii) Mortality Timepoint: 3 to 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| (i) Hospital stay (ii) Resistant organism, fungal infection Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactDr Swatantra Gupta
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed