Health Condition 1: null- Pituitary tumor
Conditions
Interventions
Intervention1: Desflurane, Propofol: Desflurane in oxygen:nitrous oxide mixture (2:1) ratio with flow rate of 2 l/min (0.8-1.2 MAC),Propofol infusion at 6-12 mg/kg/hr
BIS will be maintained between 40
Sponsors
Department of Neuroanaesthesiology and Critical Care
Dr Charu Mahajan
Dr Hemanshu Prabhakar
Dr Richa Agarwal
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged between 18-65 yr of either gender and ASA physical status I and II
Exclusion criteria
Exclusion criteria: Patients with history of previous pituitary surgery, patients with psychiatric disorder, history of drug abuse, poorly controlled hypertension, ischemic heart disease, pituitary apoplexy and history of allergy to any of the planned anaesthetic medications for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Emergence from anaesthesia, hemodynamics at various stages of surgeryTimepoint: End of surgery,hemodynamics at various stages:1.preintubation and postintubation(maximum rise within 3 minutes of intubation 2.three pin insertion(maximum rise)3.before and after nasal packing of saline swabs soaked in adrenaline (maximum rise within 3 minutes 4.preinfilteration and postinfilteration(maximum rise with 3 minutes)of nasal mucosal infiteration with lignocaine with adrenaline 5.sphenoid bone and sellar ridge dissection (maximum rise)6.after extubation(maximum rise within 3 minutes) | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse events due to technique (if any) such as hypertension, hypotension, tachycardia or bradycardiaTimepoint: during entire duration of surgery;recovery characteristics using modified aldrete score and modified version of short orientation memory concentration testTimepoint: at 5 minutes and 10 minutes after tracheal extubation. | — |
Countries
India
Contacts
Public ContactDr Devika Bharadwaj
All India Institute of Medical Sciences
Outcome results
None listed