Health Condition 1: Q213- Tetralogy of Fallot
Conditions
Interventions
Intervention1: Plain Ringer based Delnido cardioplegia solution: in pediatric patients undergoing open heart surgeries at a dose of 20ml/kg body weight mixed with patients blood in 3:1 ratio respectiv
Sponsors
Director
Eligibility
Inclusion criteria
Inclusion criteria: children in the above mentioned age group undergoing elective repair of complex cyanotic congenital heart defect with anticipated aortic cross clamp times of greater than 45 minutes will be recruited in this study.
Exclusion criteria
Exclusion criteria: 1. Emergency surgery 2. Patients with associated illnesses 3. Preoperative neurological defects 4. Other simple congenital defects and syndromes which have less than 45 minutes clamp time
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine whether the 2 types of cardioplegia solutions: Plasmalyte â??A based Del Nido or plain Ringer based Del Nido , similar in terms of surrogates of myocardial protection and morbidity and mortality.Timepoint: 48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)To assess cardiac enzyme release and/or presence of low cardiac output syndrome clinically and ionotropic score in the immediate postoperative period of 48 hours. 2)To compare the Cardiac Index of the 2 groups in the 48 hours post operative period. 3)To assess and compare for the presence of rhythm disturbances.Timepoint: 48 hours | — |
Countries
India
Contacts
Public ContactDr Sachin Talwar
AIIMS,NEW DELHI.
Outcome results
None listed