Health Condition 1: null- sepsis patients in ICU
Conditions
Interventions
None listed
Sponsors
AIIMS
Dr Dalim Kumar Baidya
Eligibility
Inclusion criteria
Inclusion criteria: 1 Sepsis patients admitted in ICU 2 Within 24 hours of diagnosis of sepsis 3 Age 18-65 years
Exclusion criteria
Exclusion criteria: 1. Patientsâ??/ their relativesâ?? refusal to consent for study. 2. Preexisting hematological disorder/ malignancy. 3. Previous history of sepsis 4. History of ICU stay within last 6 months 5. Any chronic disease, which can impair hematological system 6. History of blood transfusion in the last two weeks before ICU admission or within first three days of ICU admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To identify if parameters derived from cellular components of hematological system i.e., Hematocrit, red cell distribution width, evidence of hemolysis in peripheral blood smear, immature granulocytes,thrombocytopenia, immature platelet fraction and platelet distribution width, measured at day one of sepsis and after 72 hours (initial value and change over 72 hours) can predict 28-day mortality in adult patients with sepsis admitted to intensive care unit.Timepoint: 28 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Increased length of ICU stay, Increased number of days on mechanical ventilation, Increased requirement of vasopressor support and Increased requirement of renal replacement therapy in patients admitted to ICU with sepsis. Timepoint: 28 days | — |
Countries
India
Contacts
Public ContactHarsha Sinha
All India Institute of Medical Sciences
Outcome results
None listed