An Evaluation of Yoga Along With Multimodal Pain Management Approach And Role Of Gene Expression On Chronic Pain In Patients Undergoing Surgery For Carcinoma Breast

A Randomized-Controlled Study on Evaluation Of Yogic Intervention Along With An Integrated Multimodal Approach Using Pregabalin And Thoracic Paravertebral Block On Post Mastectomy Pain Syndrome And Expression Of Micro-Rna 133b â?? A Pilot Study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/11/010454

Enrollment

Registered

2017-11-10

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients undergoing modified radical mastectomy for carcinoma breast under general anaesthesia

Interventions

Intervention1: Group-Y: Patients undergoing modified radical mastectomy surgery will receive Yoga in the postoperative period along with multimodal pain management approach including pregabalin and th

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I â?? II patients, aged 20-65 years, undergoing modified radical mastectomy for breast cancer

Exclusion criteria

Exclusion criteria: 1. Patients with a history of seizure disorder 2. Patients with known sensitivity or contraindication to pregabalin, or on current treatment with pregabalin, gabapentin or other opioids. 3. Patients with diabetes mellitus, or with evidence of renal insufficiency. 4. Patients having cognitive dysfunction with inability to comprehend questionnaires 5. Concurrent enrolment in another yoga program

Design outcomes

Primary

Measure	Time frame
Percentage of patients with PMPS in both the groups Expression of micro RNA 133b in both the groups Timepoint: At the end of 3rd day, 30th day, 60th day, 90th day and 120th day	—

Secondary

Measure	Time frame
Details of the neuropathic component of PMPS Timepoint: At the end of 3rd day, 30th day, 60th day, 90th day and 120th day	—

Countries

India

Contacts

Public ContactDr Geetanjali T Chilkoti

University College of Medical Sciences

geetanjalidr@yahoo.co.in9711210772

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026