Health Condition 1: null- Biopsy proven Squamous Cell Carcinoma of Post- cricoid and Upper cervical esophagus
Conditions
Interventions
None listed
Sponsors
Varian Medical Systems Inc
Eligibility
Inclusion criteria
Inclusion criteria: 1.Biopsy-proven squamous cell carcinoma of the post cricoid and upper esophagus, with AJCC 7th edition stage T1-3N0-1,2M0 2.Lesions of the cervical and upper thoracic esophagus but not involving the mid and lower third of thoracic esophagus 3.Suitable for radical treatment with RT alone or Concurrent Chemo-radiotherapy 4.No significant co-morbidities that would interfere with treatment 5.Reliable for follow-up and signed informed consent. 6.Karnofsky performance status (KPS) between 70 and 100
Exclusion criteria
Exclusion criteria: 1.Age less than 18; 2.Previous treatment (e.g. chemotherapy, radiation therapy, laser therapy or surgery) for esophageal or head and neck cancer (gastrostomy or PEG does not constitute exclusion criteria); 3.Previous thoracic radiation therapy for any cause; 4.Evidence of other uncontrolled malignancies; 5.Severe compromised pulmonary function due to pulmonary disease eg. COPD 6.Scoliosis/kyphosis; 7.Failure to complete all baseline assessments required for the study. 8.Dysfunctional larynx (gross exolaryngeal extension, need for tracheostomy)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Event free survivalTimepoint: Event free survival | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute and Late toxicity Quality of lifeTimepoint: At any time | — |
Countries
India
Contacts
Public ContactDr Sarbani Ghosh Laskar
Tata Memorial Hospital
Outcome results
None listed