Health Condition 1: null- DERMATOPHYTOSES PATIENTS Health Condition 2: L088- Other specified local infections of the skin and subcutaneous tissue
Conditions
Interventions
Intervention1: SERTACONAZOLE 2% CREAM: Sertaconazole, an imidazole antifungal agent, inhibits the synthesis of ergosterol, an essential cell wall component of fungi.Sertaconazole has both fungistatic
Sponsors
Government Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1)Adults between the age group of 18 to 70 years of either gender, with clinical diagnosis and mycological confirmation (positive KOH test) for tinea corporis and tinea cruris infections, will be included in the study. 2)Patient having a Physician global assessment (PGA) composite score of at least 5 will be included in the study. 3)Patient willing to give written informed consent will be included in the study
Exclusion criteria
Exclusion criteria: 1)Patients having clinical diagnosis of tinea infections other than tinea corporis and tinea cruris, 2)Patients having extensive fungal infection, 3)Patients who had received topical or oral antifungal agents upto four weeks prior to the initiation of the study, 4)History of hypersensitivity to study drugs, 5)Immunocompromised patients, 6)Patients having superadded bacterial infection, 7)Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To Compare the efficacy of sertaconazole (2%) cream versus luliconazole (1%) cream in patients with dermatophytoses by clinical examination with the help of 4 â?? point Physician Global Assessment (PGA) scaleTimepoint: Time duration- 6 week follow up at 4th week and 6th week | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)To assess the safety and relapse in patients with dermatophytoses receiving sertaconazole (2%) cream or luliconazole (1%) cream by clinical examination , KOH mount, and monitoring adverse drug events. 2)To assess the cost effectiveness of sertaconazole (2%) cream and luliconazole (1%) cream in patients with dermatophytoses Timepoint: 6th weeks | — |
Countries
India
Contacts
Public ContactDr JAYESH MUKHI
Government medical college, Nagpur
Outcome results
None listed