Health Condition 1: null- Surgery under general anaesthesia
Conditions
Interventions
Intervention1: M 0.015: The patients will receive pretreatment with midazolam 0.015 mg/kg in a volume of 5 ml
Intervention2: M 0.03: The patients will receive pretreatment with midazolam 0.03 mg/kg in
Sponsors
University College of Medical Sciences and GTB Hospital
Eligibility
Inclusion criteria
Inclusion criteria: ASA I/II patients, of either sex, undergoing elective surgical procedures under general anaesthesia
Exclusion criteria
Exclusion criteria: Neuropsychological or neuromuscular disease, Adrenal cortical dysfunction, History of allergy to midazolam, Epilepsy, Those having received any analgesic or sedative within previous 24 hours • Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of myoclonic movements after etomidate injectionTimepoint: 60 seconds after etomidate administration | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of myoclonus after etomidate injection Changes in heart rate and mean arterial pressure after test drug Changes in heart rate and mean arterial pressure after etomidate Changes in heart rate and mean arterial pressure after intubation Incidence of airway complications e.g. laryngospasm, bronchospasm Timepoint: 11 minutes from test drug administration | — |
Countries
India
Contacts
Public ContactDr Lokman Manish
University College of Medical Sciences and GTB Hospital
Outcome results
None listed