To compare the effects of Dexmeditomidine, Esmolol, and combination of both to know the stress response prevention for endotracheal intubation.

The comparison of the effects of dexmedetomidine, esmolol and combination of dexmedetomidine with esmolol to attenuate hemodynamic response to endotracheal intubation in patients undergoing CABG.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2017/11/010355

Enrollment

120

Registered

2017-11-02

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Adult patients with ASA 1and 2 physical status scheduled for cardiac surgery

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients with ASA 1and 2 physical status scheduled for cardiac surgery

Exclusion criteria

Exclusion criteria: Exclusion criteria included anticipated difficult intubation, emergency surgery, left ventricular ejection fraction <40%, left ventricular aneurysm, associated valvular lesions, left main coronary artery disease, severe systemic diseases involving the renal and hepatic systems, preoperative left bundle branch block, chronic obstructive pulmonary disease and intubation attempt lasting longer than 20 seconds.

Design outcomes

Primary

Measure	Time frame
attenuation of stress response to endotracheal intubation in terms of heart rate, blood pressure and pulmonary artery pressureTimepoint: Hemodynamic variables(heart rate,blood pressure and pulmonary pressure) were recorded baseline, after study drug, after induction before intubation and 1, 3, 5 minute after orotracheal intubation.	—

Secondary

Measure	Time frame
nilTimepoint: nil	—

Countries

India

Contacts

Public ContactDr Shio Priye

Vydehi Institute of Medical Sciences and Research Centre

shiopriye@gmail.com9986743162

Outcome results