Health Condition 1: null- first episode unipolar depression
Conditions
Interventions
Intervention1: venlafaxine: selective serotonin and norepinephrine reuptake inhibitor
Control Intervention1: escitalopram: selective serotonin reuptake inhibitor
Sponsors
GMCH chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients of unipolar depression as per ICD-10. 2. Treatment naive patients. 3. Patients in the age group of 18-55 years. 4. Patients willing to participate in study. 5. Patients with reliable informant
Exclusion criteria
Exclusion criteria: 1. Patients of bipolar depression and recurrent depressive disorder. 2. Patients with Severe depressive episode with psychotic symptoms. 3. Patients with co-morbid substance related disorders except nicotine & caffeine. 4. Patients with subnormal intelligence. 5. Pregnant and lactating patients. 6. Any history of medical, surgical neurological complication/cognitive impairment or any other condition in which these medications are contraindicated. 7. Actively Suicidal patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| response with the minimum therapeutic dosage of the moleculeTimepoint: 2 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| assessment of response side effects and effect on cognition and quality of life with both the moleculesTimepoint: 3 months | — |
Countries
India
Contacts
Public Contactdr Ajeet sidana
Governement medical college and hospital sector 32 Chandigarh
Outcome results
None listed